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NMN (Nicotinamide mononucleotide) - Analysis Results of Third Party Laboratories

Maybe you've just heard about NMN from someone, maybe you've read Prof. Sinclair's book, or you've seen one of his many interviews on YouTube, or maybe you've come across this site through an advertisement. If so, this short video on X will give you a first impression of what it's all about.

Important notes on the (necessary) purity of NMN
The eyewash with the certificates of analysis

The end of a myth: NMN is stable at room temperature .
 

Here is the analysis of NMN (status Sept. 2020) sold by us from an independent laboratory (point 0 of our faq).
Here is an analysis from February 2023 that one of our customers had done for his safety:​ NMN-Analyse.pdf

And here the analysis of our ultra-pure NMN and here is the microbiological analysis of this NMN, which shows that we as NMN wholesaler are able to deliver pharmaceutical quality!

Here is the  microbiological analysis of NAD+ of an independent laboratory sold by us.

Here is the NR analysis of an independent laboratory sold by us.
Loyalty discount: Are you stressed and only read our emails quickly? Then please note the following: If you order frequently, you can benefit from our loyalty discount. You can find more details in each of our emails with the shipping confirmation and the tracking number.

One question worries many of our customers, especially newcomers to NMN supplementation:

Does NMN have side effects? Or is it even carcinogenic?

The issue of cooling
Is the temperature very high in your country and are you concerned whether the substances you have ordered will survive the delivery time undamaged? Then you will find a solution here! 

IMPORTANT: NMN is a chemical, not a nutritional supplement! It is not (yet) certified as such. Therefore we don't supply a  measuring spoon. If necessary, please order the inexpensive small digital scale.​ 
An important note for residents of the United States:NMN may not be sold/offered (as a dietary supplement) in the United States due to an order from the FDA (Food and Drug Administration). To avoid difficulties importing NMN just because of the name of the seller (AFEGA Anti-Aging-Shop), we recommend you to order NMN in our partner shop AFEGA Chemicals. By the way: NMN also has a beneficial effect on your beloved pet (see here a report about a dog suffering from mitochondrial disease), simply use GOOGLE-Translation for the translation: Erfolgreiche Behandlung einer schweren Erkrankung (Mitochondriopathie) durch NMN bei einem Haustier (Hund) Is it advisable to take NMN in capsules? One study showed that NMN is largely broken down in the liver as it enters the digestive tract:
https://www.cell.com/cell-metabolism/pdfExtended/S1550-4131(18)30196-7
We therefore recommend taking NMN sublingually (allowing the powder to dissolve in the lower tongue).
If you want a convenient form of dosing, choose the new lozenges we offer..

Un estudio reciente e innovador

NMN works! An exciting (human!!) study on the effectiveness of NMN!
Double-blind, placebo-controlled, the 'gold standard' for clinical trials.
The result is absolutely consistent with all of our experiences: the health-related parameters improve significantly! - However, the epigenetic age did not change, it remained constant (one might have expected it to sink) while it increased in the placebo group as expected. However, two months is a very short time and the measurement error in the methods used to determine biological or epigenetic age is actually too great to be able to make a reliable statement about the change in biological age for this short period of time. Be that as it may: NMN works !!

47 products

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250 mg NAD+ infusion (β-nicotinamide adenine dinucleotide; CAS 53-84-9) - Returns excluded! - Imported

250 mg NAD+-Infusion (β-Nicotinamidadenindinukleotid; CAS 53-84-9) - Rückgabe ausgeschlossen!
Staffelpreise!
Bei Außentemperaturen von mehr als 18 Grad wird Gekühlter Versand empfohlen! (Link anklicken und zur Bestellung hinzufügen!)
Importware (ISO 9001- und GMP-zertifiziert) - Staffelpreise
Bitte Lieferbeschränkungen für Kunden in Deutschland beachten (s. Produktbeschreibung).

€125,00
€0,50 per mg

Lieferzeit: 3-4 Tage (für CH 2 - 3 Wochen)

Styrofoam cool box for EU shipping - minimum order value: EUR 150

Lieferung in Kühlbox
Box + Zusatzaufwand

€25,00

Lieferzeit: 3-4 days

50 g ultra pure NMN powder (Nicotinamide Mononucleotide)

50 g ultra-pure NMN powder (nicotinamide mononucleotide), purity > 99%, CAS 1094-61-7
Storage: NMN is stable at room temperature and has a shelf life of AT LEAST 2 years.
The powder is currently delivered in practical plastic capsule boxes, as is common in pharmacies. If you prefer the powder to be delivered in a glass jar, as shown in the picture, please let us know in the comments field.
Please note the discount when purchasing (at least) 5 jars of U-NMN.

€59,90
€1,20 per g

Lieferzeit: 3-4 Tage

  • Sold Out

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2 ml solution in a 5 ml amber vial with 200 mg NAD (β-nicotinamide adenine dinucleotide, oxidized form; CAS 53-84-9) - return excluded!

250 mg NAD (β-Nicotinamidadenindinukleotid, oxidierte Form; CAS 53-84-9) - 2 Inj. Fl. Trs.( Doppelpack) in 2 x 10 ml - Ampulle - Rückgabe ausgeschlossen!
Bei Außentemperaturen von mehr als 18 Grad wird Gekühlter Versand empfohlen! (Link anklicken und zur Bestellung hinzufügen!)
Bitte Lieferbeschränkungen für Kunden in Deutschland beachten (s. Produktbeschreibung).

€325,00
€1,30 per mg

Lieferzeit: 2 bis 3 Wochen (für CH vor der Bestellung erfragen) - 1 x am Lager und in EU umgehend lieferbar.

250 g UTHEVER® NMN powder (500 capsules 500 mg each)

250 g NMN-Pulver, Reinheit > 99%, CAS 1094-61-7, 500 Kapseln zu je 500 mg
NMN ist bei Raumtemperatur stabil und MINDESTENS 2 Jahre haltbar. 

€275,00
€1,10 per g

Lieferzeit: 3-4 Tage

250 g liposomal NMN powder (nicotinamide mononucleotide)

250g NMN-Pulver,  Reinheit > 99%, CAS 1094-61-7
Im Kühlschrank lagern, aber nicht tiefgefrieren (Substanzen mit einem Liposom dürfen nicht tiefgefroren werden.)
Zusammensetzung:
70% NMN, 30% Phospholipid (zur Bildung des Liposoms)
Einsparpotential
Aufgrund der revolutionären Herstellungsmethode genügen anstelle der üblicherweise von Prof. Sinclair empfohlenen Tagesdosis von einem Gramm 500 mg.

€325,00
€1,30 per g

Lieferzeit: 3-4 days

  • On Sale

16 g NMN powder in a jar (Nicotinamide Mononucleotide)

16 g NMN-Pulver,  Reinheit > 99%, CAS 1094-61-7
Lagerung: NMN ist bei Raumtemperatur stabil und MINDESTENS 2 Jahre haltbar.

€17,50 €20,17
€1,09 per g

Lieferzeit: 3-4 days

1 kg betaine/TMG capsules (2000 capsules of 500 mg each) - to be taken as a precaution when consuming NMN

1 kg Betaine/TMG capsules (2,000 capsules of 500 mg each)

€149,90
€0,15 per g

Lieferzeit: 3-4 Tage

1 kg Nicotinamide powder (CAS 98-92-0)

1kg Nicotinamide powder - CAS 98-92-0

€99,90
€0,10 per g

Lieferzeit: 3-4 Tage

250 g UTHEVER® NMN powder (Nicotinamide Mononucleotide)

250g NMN-Pulver,  Reinheit > 99%, CAS 1094-61-7
Lagerung: NMN ist bei Raumtemperatur stabil und MINDESTENS 2 Jahre haltbar.
 

€249,00
€1,00 per g

Lieferzeit: 3-4 Tage

50 g UTHEVER® NMN powder (Nicotinamide Mononucleotide)

50 g NMN in Form von 400 Lutschtabletten für die bequeme Dosierung Ihres NMN
​Lagerung: NMN ist bei Raumtemperatur stabil und MINDESTENS 2 Jahre haltbar.
Inhaltsststoffe/Ingredients/Ingrédients/ingredientes/ingredienti/ингредиенты
125 mg NMN, Piperitol, Magnesium, Stearate, Silicon dioxide and Isomalt
 

€59,90
€1,20 per g

Lieferzeit: 3-4 Tage

250 g ultra pure NMN powder (Nicotinamide Mononucleotide)

250 g ultra-pure NMN (nicotinamide mononucleotide), 99.9% purity (CAS 1094-61-7)
Storage: NMN is stable at room temperature and has a shelf life of AT LEAST 2 years.
If you order more than 3 packs, please enter the discount code "u-nmn-1000" at checkout and you will receive 12% off this item.

€225,00
€0,90 per g

Lieferzeit: 3-4 Tage

250 g liposomal NMN powder (nicotinamide mononucleotide) - 500 capsules of 500 mg each

250g NMN-Pulver,  Reinheit > 99%, CAS 1094-61-7, 500 Kapseln zu je 500 mg
Im Kühlschrank lagern, aber nicht tiefgefrieren (Substanzen mit einem Liposom dürfen nicht tiefgefroren werden.)
Zusammensetzung:
350 mg NMN + 150 mg Phospholipid (zur Bildung des Liposoms)
Einsparpotential
Aufgrund der revolutionären Herstellungsmethode genügen anstelle der üblicherweise von Prof. Sinclair empfohlenen Tagesdosis von einem Gramm eine Kapsel zu 500 mg.

€360,00
€1,44 per g

Lieferzeit: 3-4 days

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2 ml solution in a 5 ml amber vial with 200 mg NAD (β-nicotinamide adenine dinucleotide, oxidized form; CAS 53-84-9) - return excluded!

125 mg NAD (β-Nicotinamidadenindinukleotid, oxidierte Form; CAS 53-84-9) - 1 Inj. Fl. Trs.( Lyophilisat) in 10 ml - Ampulle - Rückgabe ausgeschlossen!
Bei Außentemperaturen von mehr als 18 Grad wird Gekühlter Versand empfohlen! (Link anklicken und zur Bestellung hinzufügen!) -
Bitte Lieferbeschränkungen für Kunden in Deutschland beachten (s. Produktbeschreibung).

€175,00
€1,40 per mg

Lieferzeit: 2 bis 3 Wochen (für CH vor der Bestellung erfragen) - 2 x am Lager in EU und umgehend lieferbar.

Product Badge

500 mg NAD (β-nicotinamide adenine dinucleotide, oxidized form; CAS 53-84-9) - 1 injection of liquid drops in 10 ml - ampoule - Returns excluded! - EU product (EU-compliant production)

1 Inj. Fl. Trs. in einer 10 ml-Ampulle (Trs. = Trockensubstanz/Lyophilisat): Es handelt sich um ein Fläschchen, das ein gefriergetrocknetes Pulver (Lyophilisat) enthält.
Bei Außentemperaturen von mehr als 18 Grad wird Gekühlter Versand empfohlen! (Link anklicken und zur Bestellung hinzufügen!)
Bitte Lieferbeschränkungen für Kunden in Deutschland beachten (s. Produktbeschreibung).

€325,00
€0,65 per mg

Lieferzeit: 3-4 Tage (für CH aktuell 2-3 Wochen)

100 mg NAD+ infusion (β-nicotinamide adenine dinucleotide; CAS 53-84-9) - Returns excluded! - Imported

100 mg NAD+-Infusion (β-Nicotinamidadenindinukleotid; CAS 53-84-9) - Rückgabe ausgeschlossen!
Staffelpreise!
Bei Außentemperaturen von mehr als 18 Grad wird Gekühlter Versand empfohlen! (Link anklicken und zur Bestellung hinzufügen!)
Importware - Staffelpreise
Bitte Lieferbeschränkungen für Kunden in Deutschland beachten (s. Produktbeschreibung).

€49,00
€0,49 per mg

Lieferzeit: 3-4 Tage (für CH 2 - 3 Wochen)

1 kg UTHEVER® NMN in the form of 8000 lozenges for convenient dosing of your NMN

1.000 g NMN in Form von 8.000 Lutschtabletten für die bequeme Dosierung Ihres NMN
​Lagerung: NMN ist bei Raumtemperatur stabil und MINDESTENS 2 Jahre haltbar.
Bei einer Bestellung von mindestens 3 kg NMN, geben Sie bitte beim Checkout den Rabattcode "nmn-3000" ein und Sie erhalten 7,5%% Rabatt auf diesen Artikel.
Inhaltsststoffe/Ingredients/Ingrédients/ingredientes/ingredienti/ингредиенты
125 mg NMN, Piperitol, Magnesium, Stearate, Silicon dioxide and Isomalt

€1.150,00
€1,15 per g

Lieferzeit: 3-4 Tage

  • Sold Out

1 kg NR (Nicotinamide Riboside) - pure powder

1000 g NR powder (Nicotinamide Riboside Chloride), CAS 23111-00-4, purity > 98%
Please note: We no longer sell NR. However, you can purchase it through our partner shop AFEGA Chemicals .

€325,00
€0,33 per g

Lieferzeit: 3-4 Tage

Different methods of producing NMN:

1. Chemical synthesis
- Description: This method uses chemical reactions to produce NMN.
- Advantages: High yield, well suited for mass productions
- Disadvantages: Expensive, labor-intensive, use of "unnatural" raw materials, environmental pollution from solvents, difficult removal of impurities[2].

2. Enzymatic synthesis- Description: NMN is produced by enzymatic reactions, often using recombinant enzymes.
- Advantages: High purity, environmentally friendly, stable, easily absorbed.
- Disadvantages: Expensive, but considered a "green method"[2][5][7].

3. Fermentation-based biosynthesis- Description: Microorganisms such as bacteria or yeast are genetically modified to produce NMN through fermentation.
- Advantages: Environmentally friendly, cost-effective, high quality.
- Disadvantages: Low yield compared to other methods[2][3][4][6].

4. Biotechnological methods- Description: Use of genetically modified microorganisms such as *Escherichia coli* to produce NMN.
- Advantages: Cost-effective, improved yield through genetic modifications.
- Disadvantages: Complex optimization of production conditions required[3][7].

5. Cascade catalysis- Description: Multiple enzymes are used in a cascade to synthesize NMN.
- Advantages: Efficient production, high purity.
- Disadvantages: Complex process control[8].

The choice of production method depends on various factors, including cost, environmental impact, yield and purity of the final product. Enzymatic and fermentation-based methods are increasingly preferred as they are more environmentally friendly and sustainable[2][3][5][7].

Sources:
[1] https://patents.google.com/patent/WO2019065876A1/en
[2] https://getwonderfeel.com/how-nmn-manufactured/
[3] https://www.mdpi.com/2311-5637/9/7/594
[4] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418623/
[5] https://pubs.acs.org/doi/abs/10.1021/acs.jafc.3c09217
[6] https://www.nature.com/articles/s41598-021-87361-1
[7] https://pubmed.ncbi.nlm.nih.gov/30115969/
[8] https://pubs.rsc.org/en/content/articlehtml/2023/ra/d3ra03857b?page=search

Different methods of manufacturing NMN cause the resulting NMN product to differ in properties such as color, density, taste and other characteristics.The main reasons for this are:1. Purity level- Depending on the production method, different amounts of impurities or byproducts may be present in the NMN, which can affect the color and taste.
- For example, chemically synthesized NMN may contain more impurities than enzymatically or fermentatively produced NMN.

2. Crystal structure- Crystallization conditions during manufacturing can change the crystal structure and thus the density of the NMN powder.
- Different crystal forms (polymorphic forms) can have different densities.

3. Particle size- Depending on the grinding and sieving, the particle size of the NMN powder can vary.
- Finer particles have a higher density than coarser ones.

4. Residual moisture- The moisture content of the NMN powder after the drying process can vary.
- Higher residual moisture leads to a lower density.

5. Additives- Some manufacturers add release agents, fillers or binders, which can affect color and taste.

The NMN of the AFEGA® brand:

We do not always purchase our own brand NMN from the same producer. We want to be able to offer this NMN as cheaply as possible and therefore negotiate the price with various producers. If the quality (especially the purity) meets our requirements, we then order from the producer who can deliver at the cheapest price.

Customers who care about the properties of the NMN always being exactly the same then order the NMN of the UTHEVER brand and accept the slightly higher price.

However, the higher price is not related to a difference in quality! It is accepted by people who are either particularly fond of the brand and have good associations with UTHEVER or EFFEPHARM, or who feel better when the substance always has exactly the same properties.