David Sinclair explains the effects of sirtuins as follows:

1. Activation of sirtuins: Sinclair emphasizes that sirtuins are enzymes that are thought to slow down aging. These enzymes can dampen the activity of certain genes that are responsible for aging[3][4].
2. Antioxidant effect: Sirtuins have antioxidant properties that can help reduce oxidative stress and inflammation in the body[4].
3. Connection to resveratrol: Sinclair explains that resveratrol, a natural substance found in peanuts, berries and grapes, activates sirtuins. This activation can lead to an extension of lifespan and improved health[1][3][5].
4. Synergy with NMN: Sinclair emphasizes the synergy between resveratrol and NMN (nicotinamide mononucleotide). While resveratrol activates the sirtuins, NMN is needed to feed these proteins and support their function[4].

Sources:
[1] https://www.focus.de/gesundheit/gesundleben/antiaging/lifestyle/neue-formeln-gegen-das-altern-medizin_id_2166072.html
[2] https://www.spiegel.de/wissenschaft/medizin/vermeintliche-jungbrunnen-pillen-geschaeft-mit-dem-leben-a-722026.html
[3] https://www.zeit.de/zeit-wissen/2010/06/Resveratrol
[4] https://www.schweizer-illustrierte.ch/body-health/toyota/die-experten-tipps-fur-ewige-jugend-im-reality-check
[5] https://deutsch.medscape.com/artikel/4900856

In addition to resveratrol, other substances activate the sirtuins. These substances are:

1. Curcumin: A polyphenol found in turmeric that acts as a direct sirtuin activator[4].
2. Quercetin: A flavonoid found in apples and other plant foods that activates sirtuins[4]. (Also available in our store.)
3. Cocoa flavonoids: These flavonoids are found in dark chocolate and act as sirtuin activators[4].
4. Anthocyanins: These pigments are found in blueberries and raspberries and activate sirtuins[4]. (See our product "Pterostilbene: The blueberry molecule")

Sources:
[1] https://www.focus.de/gesundheit/gesundleben/antiaging/lifestyle/neue-formeln-gegen-das-altern-medizin_id_2166072.html
[2] https://www.zeit.de/zeit-wissen/2010/06/Resveratrol
[3] https://deutsch.medscape.com/artikel/4900856
[4] https://www.ugb.de/ugb-medien/einzelhefte/gesunder-dreiklang-koerper-psyche-geist/was-sind-sirtuine-und-wie-ist-die-sirtfood-diaet-einzuschaetzen/
[5] https://www.spiegel.de/wissenschaft/medizin/vermeintliche-jungbrunnen-pillen-geschaeft-mit-dem-leben-a-722026.html

The eyewash with the certificates of analysis

Here is the Resveratrol analysis of an independent laboratory sold by us.

Here is the Pterostilbene analysis of an independent laboratory sold by us.As a result of a new study, Sinclair advises against taking resveratrol capsules or powder on days when you exercise intensely. However, he finds resveratrol so valuable that he does not want to omit it completely: ClickFundamental criticism and doubts about the anti-aging effect of resveratro lHere is an article in the German medical journal, which comes to a positive assessment of resveratrol and casts doubt on the studies cited in the YouTube video.

This study from 2021 shows many beneficial effects of resveratrol: A promising "all-rounder" among secondary plant substances Study from 2022: ​Resveratrol promotes wound healing